What is chromophobe renal cancer?

An unusual type. This is a rare type of kidney cancer. It is usually found at an early stage and has a better prognosis generally than other kidney cancers.
Chromophobe renal ca. It is a subtype of renal cell carcinoma.These are relatively rare 3-5% of all all kidney cancers.
Chromophobe. Chromophobe renal cell carcinoma makes up a small percentage of kidney cancers (about 5%). It is named that -"chromo" = color or stain and "phobe" = fear of, because typically it has a characteristic appearance under the microscope of cells that are pale-staining with the dyes used in pathology. The prognosis is often considered better than other types of renal cell carcinoma.

Related Questions

What makes the prognosis for chromophobe renal cancer better than other renal cancers?

Molecules. It arises by a completely different molecular pathway than do common kidney cancers. We're still working out the details. Read more...
Not entirely clear. Chromophobe tumors arise from a specific type of kidney cell (cortical collecting duct) and exhibit a pattern of genetic changes that can differ from other renal cancers. Most studies of chromophobe tumors suggest a better prognosis for localized tumors and delayed appearance of metastatses, but a subset of patients with high-grade features can have poor outcome. Read more...

How is chromophobe renal cancer different from others?

Many ways. The prognosis is better than for a common kidney cancer, their pattern of immunostaining is very different, they tend to spread to liver rather than where other kidney cancers usually go, and there is even a genetic mutation that can make them common in one family. Read more...
Better prognosis. Generally speaking, chromophobe carcinomas behave less aggressivley stage for stage than other types. Read more...

What are considered high grade features for chromophobe renal cancer?

See pathology report. Am. J. Surg. Path 2011 deals with unfavorable features and while traditional grading systems have been tried, the latest work shows that only necrosis, sarcomatoid features, being quite large, and having tumor in small vessels warn of a less favorable prognosis. Read more...
Fuhrman grade. The fuhrman grading system is the most widely accepted system of grading kidney cancer. It ranges from 1 to 4, with 1 and 2 considered low grade while 3 or 4 are considered high grade. Read more...

What does it mean that the prognosis for chromophobe renal cancer is favorable. I have read this in many different articles.?

Outcome is good. Overall, this means that the outcome for this is good compared to other conditions, or at least, other renal cancers. This cancer is less likely to spread or less aggressive than other kidney cancers, and so survival is improved. Read more...
Likely to be cured. This has been discussed before but this is a less agressive variation of kidney cancer. It is uncommon. Most patients are found with a very early stage and many patients do well. In medicine, tumors don't always "read the book" and do what they are supposed to do. So there are some bad outcomes for this tumor. We doctors use word like favorable just in case. Read more...

What are ther any doctors that have had experience with treating chromophobe renal cancer in melbourne?

Is a rare tumor. accounts less than 5% of kidney tumors , besides its characteristic histological appearance , some times genetically related , could be bilateral , surgical procedure will be same , ask your oncologist who will give you the best options and if necessary will refer you to a large centre near you. Read more...

Is there a difference in the prognosis for typical and eosinophilic variant of chromophobe renal cancer?

Yes. Chromophobe renal cell carcinomas are classified into typical and eosinophilic variants depending on the predominant cell type. The evcrcc is not as common as the typical variant and is likely to be mistaken for oncocytoma because of the predominance of type i cells and hence the significance. The eosinophilic variant has been reported to have a better prognosis than typical variant. Read more...

Are there any therapies on the horizon to prevent the reoccurrence of chromophobe renal cancer? Any clinical trails currently taking place?

Advances in chemo. Chromophobe renal cancer accounts 5% of renal cancers, early detection and treatment has excellent prognosis. If there is over expression of cd 117 on cell membrane , kinase inhibitors like imatinib, disratinib, and nilotinib are very effective. Best thing is to see an oncologist, for more recent medications or trails. Read more...

What is renal cancer spread?

METASTASIS. When kidney cancer spreads it goes to the nearby lymph nodes first. If it further spreads it tends to go to the bones or lungs. Kidney cancer is treated initially surgically. When it spreads there are several oral medications to control the cancer. Read more...

What could cause renal cancer?

Many things. Smoking, high blood pressure, obesity, exposure to toxic substances, overuse of pain relievers, and cystic changes of the kidneys are risks for getting renal cancer. Cadmium, asbestos, and petroleum-based chemicals (like de-greasers) are the main toxins that cause renal cancer. Chronic hepatitis c infection is linked to causing kidney cancer. There is a strong genetic link as well. Read more...
Smoking. Cigarette smoking is associated with many cancers including renal cancer. Certain inherited disorders may also increase the risk of developing kidney cancer. Read more...