How does Zoloft (sertraline) work?

Zoloft (sertraline) Zoloft (sertraline) is one of selective serotonin reuptake inhibitors, hence produces elevation in serotonin levels which produce reduction in symptoms of depression & anxiety.
Zoloft (sertraline) Sertraline (Zoloft/ Lustral) is one of the Selective serotonin reuptake inhibitor (SSRI) antidepressants. It works primarily by increasing serotonin. It is is FDA approved for the treatment of major depressive disorder, panic disorder, social anxiety disorder, post traumatic disorder, obsessive compulsive disorder, premenstrual dysphoric disorder and body dysmorphic disorder.

Related Questions

How effectively does Zoloft (sertraline) work for anxiety, insomnia and does it cause weight loss?

Zoloft (sertraline) Zoloft (sertraline) can be very effective for treating anxiety. Insomnia can occur occassionally as a side effect. When that happens, i usually recommend that it be taken in the morning. It can cause weight loss or gain (but weight gain is more common). Read more...

What works after Zoloft (sertraline) fails?

Varies. Antidepressant failure for depression would be no response t an adequate dose for 6 to 8 weeks. There are different classes of antidepressants, and while some may respond to an antidepressant in the same class as the one just tried, often it is helpful to try one of a different class. Cognitive behavioral therapy can also be very helpful. Please speak to the your physician regarding options. Read more...
Zoloft (sertraline) Insure that the zoloft trial is adequate. What condition is being treated? For depression, other SSRI's can be tried as well as mood stabilizers. Abilify (aripiprazole) can be used to augment zoloft for depression. For anxiety there are benzodiazapines and buspar. Consider cognitive behavioral therapy, behavior therapy or psychotherapy. Exercise, healthy diet, adequate sleep, yoga, meditation, tai chi, etc. Read more...

Does the time of day that I take my Zoloft (sertraline) make any difference on how well it works?

Not really. Timing of doses depends on the person. Some find zoloft (sertraline) a bit sedating, and prefer to take it at bedtime. Others for whom it is activating, take it in the morning. Pick a time each day that suits you best. Read more...
No. Zoloft (sertraline) stays in your system for ~24 hours, so it doesn't matter when you take it. It is best to take it at the same time consistently. At higher does (150-200mg) it can be mildly activating and to not interfere with your sleep it can be best to take first thing in the morning. Read more...
Zoloft (sertraline) I recommend taking it the same time every date with food. Read more...

If taking Zoloft (sertraline) is lnt working as well as I want it to work, what would be te benefits of switching to an ssnri?

Unknown. Zoloft (sertraline) is an ssri, it seems its helping but not as much as you want to, discuss with your doctor , he may switch you to another ssri, or switch to an snri. We need more history to advice.Ssri mostly works on serotonin, while snri works more on Dopamine and norepinephrine, but each brand has its pro s and cons. Best discuss with your doctor. Read more...

I have been on Zoloft (sertraline) for 6 weeks 150 mgs. I still dont feel good. Do u think that possibly 200 mgs will work. Isee the dr tomorrow?

Already pretty high. 200mg is the maximum safe dose, so you're pretty high already. If it's not causing any problems and works pretty well, a bit more may be okay - but if it's not doing good and is doing harm, increasing will only make w/drawal harder. A change or adding talk therapy might be a better strategy. Think about how you manage things and if you can do better. Tx + Rx is often the best solution. Read more...

I just started taking Zoloft (sertraline) 50mg for five weeks. I'm still dealing with worry feelings at work mostly. Should I still continue taking.?

Continue for now! This is not a medication to stop on your own - you need a Dr to guide you through a taper off and be aware of any bad reactions. So call the Dr to describe your situation and ask your questions. Don't just stop! Read more...