3 doctors weighed in:

How does multiple sclerosis affect the hypothalamus?

3 doctors weighed in
Dr. Brad Bobrin
Psychiatry
1 doctor agrees

In brief: It shouldn't

Since the hypothalamus is not really a white matter structure, it should not effect thje hypothalamus directly but it could effect neurons that go into and leave the hypothalamus.
Since thie hypothalamus controls temperature, feeding behavior, sexual behavior and heart rate and blood pressure, if a brain region needs input from the hypothalamus it may not get it.

In brief: It shouldn't

Since the hypothalamus is not really a white matter structure, it should not effect thje hypothalamus directly but it could effect neurons that go into and leave the hypothalamus.
Since thie hypothalamus controls temperature, feeding behavior, sexual behavior and heart rate and blood pressure, if a brain region needs input from the hypothalamus it may not get it.
Dr. Brad Bobrin
Dr. Brad Bobrin
Thank

In brief: FATIGUE AND SLEEP

This is a complex question.
We are finding that sleep disorders, such as narcolepsy and restless leg syndrome can be associated with ms, and some research suggests that hypocretin-i secreting cell loss may well be autoimmune. Although not usually recognized, interferon-beta meds do cause fatigue secondary to hypothalamic effects. Congrats, your question is highly sophisticated.

In brief: FATIGUE AND SLEEP

This is a complex question.
We are finding that sleep disorders, such as narcolepsy and restless leg syndrome can be associated with ms, and some research suggests that hypocretin-i secreting cell loss may well be autoimmune. Although not usually recognized, interferon-beta meds do cause fatigue secondary to hypothalamic effects. Congrats, your question is highly sophisticated.
Dr. Bennett Machanic
Dr. Bennett Machanic
Thank
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