Wash your hands. Sepsis is not in itself "avoidable" - but you can ensure good general health by eating well, avoiding steroids, and washing your hands. Keeping yourself from getting shot, stabbed or crushed is also a good idea, and keeping dirt out of your wounds is a bonus. If you are diabetic, take your Insulin or other medications and follow a sound diabetic diet.
Wash your hands. Prevent sepsis by preventing infection--hand washing is the single best thing we can do to prevent infection. Getting the flu vaccine is also important ( for more details, check out: http://www.Cdc.Gov/flu/protect/keyfacts.Htm ) as well as childhood vaccinations ( http://www.Cdc.Gov/vaccines/recs/schedules/child-schedule.Htm ). There's not enough space to discuss all prevention strategies.