3 doctors weighed in:

Does rheumatoid arthritis always show up in blood work?

3 doctors weighed in
Dr. Pierre Moeser
Internal Medicine - Rheumatology
1 doctor agrees

In brief: Possible negative

Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis.
Other tests are done to measure inflammation, determine which drugs may be used, etc. About 15% of people with RA are rf and ccp negative.

In brief: Possible negative

Rheumatoid factor (rf) and cyclic citrinullated peptide (ccp) are the two tests that help confirm a diagnosis of rheumatoid arthritis.
Other tests are done to measure inflammation, determine which drugs may be used, etc. About 15% of people with RA are rf and ccp negative.
Dr. Pierre Moeser
Dr. Pierre Moeser
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Dr. Michael Laccheo
Internal Medicine - Rheumatology

In brief: No

If you mean are the antibodies associated with rheumatoid arthritis (ccp and rf) always positive in rheumatoid arthritis, no.
About 15% of patients are "seronegative." usually there are some abnormalities though such as elevated inflammatory markers, anemia, elevated white count or elevated platelets. But not always.

In brief: No

If you mean are the antibodies associated with rheumatoid arthritis (ccp and rf) always positive in rheumatoid arthritis, no.
About 15% of patients are "seronegative." usually there are some abnormalities though such as elevated inflammatory markers, anemia, elevated white count or elevated platelets. But not always.
Dr. Michael Laccheo
Dr. Michael Laccheo
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