Autoimmune. Polymyalgia rheumatica (pmr) is an autoimmune disease that occurs in people 50 years of age and older. It is associated with severe pain and stiffness in the shoulders and hips. Pmr can also lead to blindness due to inflammation in blood vessels of the eye. Pmr is treated with steroids and Aspirin to prevent blindness. Other medicines (antibiotics) are sometimes used to prevent steroid effects.