9 doctors weighed in:

Are there any known causes for imperforate anus?

9 doctors weighed in
Dr. James Ferguson
Pediatrics
5 doctors agree

In brief: Poor signals

The imperforate anus can occur in isolation or as part of a syndrome.
During fetal development the gut starts as a sausage like mass that forms a central cavity, lengthens & moves down from the inside to join up with the external skin at the anus. The defect can be as minimal as a thin membrane in normal position or gut ending far from the anus. Poor signal decoding triggers this defect.

In brief: Poor signals

The imperforate anus can occur in isolation or as part of a syndrome.
During fetal development the gut starts as a sausage like mass that forms a central cavity, lengthens & moves down from the inside to join up with the external skin at the anus. The defect can be as minimal as a thin membrane in normal position or gut ending far from the anus. Poor signal decoding triggers this defect.
Dr. James Ferguson
Dr. James Ferguson
Thank
1 comment
Dr. Carla Enriquez
Once again a great answer!
Dr. Nikolaos Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
3 doctors agree

In brief: Down, VACTER-L.

Anal atresia is most commonly associated with the vacterl association (vertebral, anal atresia, cardiac, tracheoesophageal fistula, renal, limb anomalies), and occurs with increased frequency in trisomy 21 (down syndrome).

In brief: Down, VACTER-L.

Anal atresia is most commonly associated with the vacterl association (vertebral, anal atresia, cardiac, tracheoesophageal fistula, renal, limb anomalies), and occurs with increased frequency in trisomy 21 (down syndrome).
Dr. Nikolaos Zacharias
Dr. Nikolaos Zacharias
Thank
Dr. Troy Reyna
Surgery - Pediatric
1 doctor agrees

In brief: No

There are no genetic causes known for imperforate anus or other factors like drugs or illnesses that can happen while pregnant.

In brief: No

There are no genetic causes known for imperforate anus or other factors like drugs or illnesses that can happen while pregnant.
Dr. Troy Reyna
Dr. Troy Reyna
Thank
Read more answers from doctors