Sometimes. Rai stage 0 cll infrequently progresses to higher-stage disease. The median survival is at least 130 months as reported in 2009: http://asheducationbook. Hematologylibrary. Org/content/2009/1/421/t2.Expansion. Html the disease is "heterogeneous, " which means that different patients have different experiences, making progression hard to predict in any one individual.
It can. But typically depends on few specific abormalities we find by molecular analysis such as fish analyss, it in general stage 0, may just do fine, but can progress to advanced stage late future, usually many years.