Is there a link between pernicious anemia and cancer?

Possibly. There appears to be some association between pernicious anemia and the risk of developing gastric cancer, but this is controversial. Pernicious anemia frequently develops with an autoimmune attack on certain gastric cells, which leads to vitamin B12 deficiency and later anemia. This autoimmune attack also leads to chronic gastritis, which can then progress to cancer.
Possible link. People with pernicious anemia maybe at risk for developing gastric polyps, gastric carcinoid tumors and gastric cancer. Individual risk should be established by consulting with a gastroenterologist and an oncologist.

Related Questions

I have pernicious anemia and take b-12 shots. I also have had full hysterectomy. I take hormones, pill form. Do I need the hormone in shot form?

No , no need to. No i don't thing so. But you should d/w your gp or gyne. Make sure you understand there is a little increase risk for breast cancer that was related to hormonal replacement- especially with the use of progesterone. Age appropriate cancer screening is recommended. Read more...

What symptoms of pernicious anemia are the most common?

Fatigue. In pernicious anemia, there is no vitamin B12 absorption which causes low red blood cell production and leads to severe anemia. This causes fatigue most comonly. Read more...

Does methadone cause pernicious anemia?

Not likely. Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. Read more...

Is it true that leukemia and pernicious anemia the same thing?

Not at all. Pernicious anemia results from poor dietary uptake of vitamin b12, usually from a loss of certain cells in your stomach. These cells secrete intrinsic factor, necessary for absorption of vitamin b12. Treatment is B12 shots, potentially. Leukemia is cancer. Treatment is chemotherapy. Read more...

What's the difference between pernicious anemia and B12 anemia?

See below. B-12 anemia is a deficiency in vitamin b-12 (cobalamin). Pernicious anemia is a deficiency or lack in intrinsic factor (produced by cells in the stomach) which is a protein essential for absorption of vitamin B12 in the ileum (small intestine). Pernicious anemia requires replacement of intrinsic factor &/or b-12. B-12 anemia needs only b-12 supplementation. Read more...

Please explain what happens to people who have pernicious anemia but are intolerant to b12?

Can you clarify? If you have pernicious anemia and aren't effectively treated, you will first lose your mind and then your life. If by "B12 intolerance" you simply mean you cannot absorb the vitamin orally, this is common and you'll need monthly injections. If you believe that the supplement makes you sick -- as it claimed on some "pop" websites -- I'm skeptical but you'll need to get specialist consultation. Read more...