Is pernicious anemia life-shortening?

Typically not. Pernicious anemia when treated with life long B12 replacement confers a normal lifespan. There is an increased risk of stomach cancer in some cases which can affect survival times.
Should not be! It did shorten lives. But with B12, there should be no shortening of life!!!!!!!!!!!!!!!!!!!
See below. Pernicious anemia results from the inability to absorb vitamin B12 normally due to a lack of intrinsic factor, a substance required for adequate B12 absorption. This leads to macrocytic anemia; large red blood cells. It is no longer "pernicious" as it is easily treated with either large doses of oral vitamin B12 , or injectable vitamin b12. It is not life shortening.