How does pernicious anemia cause people to have achlorhydria?

The other way around. Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia.
Common cause. Both pernicious anemia (inability to absorb vitamin b12) and achlorhydria (inability of the stomach to make acid) result from the same underlying problem -- autoimmune destruction of the inner mucosal lining of the stomach ("autoimmune atrohpic gastritis").

Related Questions

Does pernicious anemia cause high serum b12?

Low vitamin B12. pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. Read more...

Does methadone cause pernicious anemia?

Not likely. Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. Read more...

Can alcoholism cause you to have pernicious anemia?

Yes. Alcoholics usually do not take in adequate amounts of Folic Acid which can lead to megaloblastic anemia. B12 deficiency is less common but possible as well. Read more...
Yes. Malnourishment, as can be the case with some alcoholics who have very poor diets, can result in vitamin b-12 deficiencies which contribute to pernicious anemia. Alcohol, bu itself can lead to different forms of blood count abnormalities as well, such as low white blood cell counts and low platelet counts. Also, thiamine deficiencies can cause irreversible brain damage called wermicke- korsakoff. Read more...
No. PA is an autoimmune disorder in which the stomach fails to produce "intrinsic factor" resulting in very low Vit. B12. Alcoholism may be associated with various nutritional deficiencies by other mechanisms. Pernicious anemia is a specific condition not related to alcohol. Read more...

What are the causes of symptoms in pernicious anemia?

Lack of vitamin B12. Pernicious anemia is due to a lack of vitamin b12. B12 is necessary for the normal function of the nervous system and the formation of red blood cells. Read more...
Vitamin B12. Deficiency causes both the hematologist and neurological symptoms of pernicious anemia. B12 and folate (folic acid) supplements can be corrective. Work with your dr. To address this problem. Read more...