3 doctors weighed in:

Will progesterone cream help with peri-menopausal symptoms like depression, anxiety?

3 doctors weighed in
Dr. Gerard Honore
Fertility Medicine
2 doctors agree

In brief: Unlikely

In my clinical experience it is highly unlikely, although individual results might vary.
It can't hurt to try for a short while, but don't expect a miracle. Further, be aware the otc 'progesterone creams' rarely contain any actual Progesterone (especially the mexican yam extracts, ) and the amount and bioavailability is pretty unreliable - sorry to say.

In brief: Unlikely

In my clinical experience it is highly unlikely, although individual results might vary.
It can't hurt to try for a short while, but don't expect a miracle. Further, be aware the otc 'progesterone creams' rarely contain any actual Progesterone (especially the mexican yam extracts, ) and the amount and bioavailability is pretty unreliable - sorry to say.
Dr. Gerard Honore
Dr. Gerard Honore
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