Can multiple myeloma affect the liver?

Yes. Not common. Yes. Multiple myeloma can effect any organ. However, liver involvement is not common. Myeloma generally involves the bones predominantly; however there are reports of nearly every organ being involved in including the brain. Liver involvement by any cancer can make some types of chemotherapy (that is processed by the liver) more difficult to give.
Rarely but yes. Multiple myeloma is a plasma cell disorder primarily effecting bone marrow. In the solitary version an occasional lesion is seen in soft tissue such as pharynx. Liver involvement is very rare, the most common presentation being in the form of amyloidosis or cholestatic jaundice. Clonal selection after thalidomide treatment might be one cause. In practice the incidence of liver lesions is les.

Related Questions

In what way is the liver is affected by multiple myeloma?

It is usually not. Usually myeloma doesn't attack the liver but many of the drugs we use to treat it do have effects on the liver. Also, a related type of cancer called amyloidosis can invade the liver and other organs and interfere with their function. Read more...
Usually not. The liver is not usually affected by myeloma however clusters of myeloma cells can rarely deposit in the liver. These are called plasmacytomas. Read more...

Mom has liver cancer and now multiple myeloma? When can she be cured?

Chemotherapy. Sorry bad combination, see your family physician for referral to an oncologist. Great chemotherapeutic agents are available now to achieve a good palliation. Read more...
Unfortunate. It is with regret that I have to state that neither liver cancer nor multiple myeloma are generally curable cancers. Liver and bone marrow transplants may offer hope if a person has only one. Read more...

My 80 yr husband has multiple myeloma. He won't eat. Can walk, but lies in bed or couch all day. Dr. will not discuss 'stage'. I know he is failin?

Get new doc. If your doc cannot or will not explain the stage / prognosis and treatment of your condition in terms you can understand you really should find a different doctor. MM is common and well studied - treatments, staging and prognosis are fairly well defined. Read more...
2nd opinion v hospic. Check out http://www.mayoclinic.org/diseases-conditions/multiple-myeloma/basics/treatment/con-20026607 for info on multiple myeloma and its treatments. Get a 2nd opinion (or change physicians - your Family Doc can help you find Oncologist who accepts your/his insurance). If no treatment is desired, consider hospice for comfort/palliative care. Again, your Family Doc can refer or you can ask on own. Read more...