6 doctors weighed in:
Is multiple myeloma genetic?
6 doctors weighed in

Dr. Edward Gold
Internal Medicine
2 doctors agree
In brief: No
Myeloma does not appear to have a genetic predisposition.

In brief: No
Myeloma does not appear to have a genetic predisposition.
Dr. Edward Gold
Dr. Edward Gold
Thank
Dr. Michael Thompson
Internal Medicine - Hematology & Oncology
1 doctor agrees
In brief: Yes/No
In a sense all cancer is "genetic" involving changes to the DNA or epi-genetic - changes to DNA modifiers such as methylation.
A related question is is multiple myeloma inherited. The answer is sometimes. The risk is about double with a family history. Here is one clinical trial studying this: https://clinicaltrials.gov/ct2/show/NCT00582621

In brief: Yes/No
In a sense all cancer is "genetic" involving changes to the DNA or epi-genetic - changes to DNA modifiers such as methylation.
A related question is is multiple myeloma inherited. The answer is sometimes. The risk is about double with a family history. Here is one clinical trial studying this: https://clinicaltrials.gov/ct2/show/NCT00582621
Dr. Michael Thompson
Dr. Michael Thompson
Thank
3 comments
Dr. Michael Thompson
Family Study of Lymphoproliferative Disorders - https://clinicaltrials.gov/ct2/show/NCT00626496
Dr. Michael Thompson
Clinical, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Hematologic Cancer - https://clinicaltrials.gov/ct2/show/NCT00039676
Dr. Liawaty Ho
Internal Medicine - Hematology & Oncology
1 doctor agrees
In brief: Likely Not
There is no clear genetic predisposition in multiple myeloma.
Rather, older age, immunosuppression, and environmental exposures to radiation, benzene, and other organic solvents, herbicides, and insecticides are potential risk factors for multiple myeloma.

In brief: Likely Not
There is no clear genetic predisposition in multiple myeloma.
Rather, older age, immunosuppression, and environmental exposures to radiation, benzene, and other organic solvents, herbicides, and insecticides are potential risk factors for multiple myeloma.
Dr. Liawaty Ho
Dr. Liawaty Ho
Thank
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