5 doctors weighed in:

Does metformin cause megaloblastic anemia?

5 doctors weighed in
Dr. Susan Wingo
Internal Medicine - Endocrinology
2 doctors agree

In brief: It can

Megaloblastic anemia is caused by a deficiency in vitamin B12 or folic acid.
Taking metformin can cause your body to "use up" vitamin b12, and become deficient in b12, which, in severe cases, could lead to megaloblastic anemia. This can usually be corrected with a vitamin B12 pill, unless there is also a problem with absorbing b12.

In brief: It can

Megaloblastic anemia is caused by a deficiency in vitamin B12 or folic acid.
Taking metformin can cause your body to "use up" vitamin b12, and become deficient in b12, which, in severe cases, could lead to megaloblastic anemia. This can usually be corrected with a vitamin B12 pill, unless there is also a problem with absorbing b12.
Dr. Susan Wingo
Dr. Susan Wingo
Thank
Dr. Steven Ginsberg
Internal Medicine - Hematology & Oncology
1 doctor agrees

In brief: No

Metformin does not cause megaloblastic anemia.
Diabetics are frequently anemic for a variety of reasons.

In brief: No

Metformin does not cause megaloblastic anemia.
Diabetics are frequently anemic for a variety of reasons.
Dr. Steven Ginsberg
Dr. Steven Ginsberg
Thank
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