Should I pop the blister from a red ant bite?

Only if it is tense. Usually we don't recommend popping blisters, as the intact skin prevents infection. The fluid will generally resolve on its own. If the blister is tense and painful though, it can be helpful to drain the fluid. I would try to keep the skin intact as much as possible. And cover the wound with a bandage.
Use ice. I would apply ice compress to the area. Put some ice cubes or crushed ice in a ziploc bag and put it on the ant bite for 20 mins, then leave ice off for 20 minutes, then reapply ice. Do this several times a day and it should help.

Related Questions

How does a red ant bite blister burst if you don't pop it?

No need to burst. It gradually dries up and goes away. Popping it puts you at increased risk for infection. Read more...

Skin bumps with an ant-bite like inflammation with itching and end up in red tiny blisters after sometime with reduced itching. Started from my leg.

Of course first ? is where were you recently, as this certainly could be a bite reaction. But other conditions can cause bite like inflammation including something simple like folliculitis. I would see a dermatologist for diagnosis and treatment. Read more...
This sounds like a skin condition related to dry skin. Look up" hyperkeratosis pilaris" in Google and then switch to the images and see if the picture looks like you're rash. If it appears to be a match then you need to do quick bathing so as not to dry out the skin and use a lot of lotion. Read more...