Could hydrea (hydroxyurea) possibly help children with sickle cell disease?

Yes. Hydre increases a type of hemoglobin called fetal hemoglobin in sicle cell patients and this prevents the sickle cells from breaking up easily. Hydrea (hydroxyurea) can reduce need for transfusions and patients may have less pain crises, chest sydrome and other complications.
Yes. Hydroxyurea, hydrea, (hydroxyurea) is well known in several large multi-institutional national studies to help children that have sickle cell disease. Particularly in children that have had prior sickle cell crises, Hydroxyurea appears to have benefits in reducing the frequency and severity of sickle cell crises.

Related Questions

Can hydrea (hydroxyurea) be used to help children with sickle cell disease?

Yes. In the treatment of sickle-cell disease, hydroxycarbamide increases the concentration of fetal hemoglobin. The precise mechanism of action is not yet clearbut it seems to activate of gammaglobin synthesis necessary for fetal hemoglobin. This stops the rapidly growing cells that turn into sickle cells. Read more...
Under supervision. Yes used in children also under medical supervision , help better capillary blood flow speak to the treating pediatrician. Read more...

What are the symptoms of sickle cell disease- hydroxyurea?

Well tolerated drug. Hydrea (hydroxyurea) is a chemotherapy like drug that can help prevent painful crises in patients with sickle cell disease. It is well tolerated for the most part. There can be fatigue, mouth sores and loose stools. It will routinely lower the white blood cell count and platelets, but not to dangerous levels. Hemoglobin may actually improve. There is ? Of leukemia risk in other diseases, but not in scd. Read more...

What are the effects of a sickle cell patient using hydroxyurea in the long term?

Side Effects. There are some serious, but rare, side effects with hydroxyurea, including secondary leukemia, pulmonary fibrosis, pancreatitis, and peripheral neuropathy, or damage to the nerves. Discuss the benefits of decreasing the severity and length of the sickle cell attacks, and the risk of rare side effects as above. Read more...
Minimal to none. When Hydroxyurea is taken as prescribed and follow up labs are obtained and monitored, few long term complications of hydtoxyurea therapy have been reported. It is important to get the follow up labs to monitor your blood count and liver function so that the dose can be adjusted if needed. The benefits of Hydroxyurea therapy have been well documented and many consider it standard of care. Read more...

I have sickle cell and I'm taking hydroxyurea, but I'm still having frequent crisis and hospital visits, does it not work for all patients?

Sometimes. It does not work for all patients, but it also does not work right away. Work with a hematologist to increase your dose of hydroxyurea to the maximum tolerated to increase your chances of increasing Fetal Hemoglobin [HbF] production (the goal of Hydrea is to make HbF instead of sickle hemoglobin) . Best wishes. Read more...

What precautions should I take to decrease the episodes of crisis in sickle cell. I take folic acid & hydroxyurea as medication.

Hydration. Besides taking your medication, the most important thing you can do to reduce sickle crisis is to keep yourself well hydrated. You need to be exceeding 80 oz of water daily. Even the least little dehydration can lead to increased viscosity (thickness) of your blood, and this in turn can lead to increased sickling and a full-blown crisis. Avoid dehydrating things like sun, alcohol and caffeine. Read more...