2 doctors weighed in:

Does it matter if I take simvastatin in the morning or at bedtime?

2 doctors weighed in
Dr. Julian Javier
Internal Medicine - Cardiology

In brief: When to take statin

Best time to take statins which is a medication for cholesterol is one hour before dinner.

In brief: When to take statin

Best time to take statins which is a medication for cholesterol is one hour before dinner.
Dr. Julian Javier
Dr. Julian Javier
Thank
Dr. Irv Loh
Internal Medicine - Cardiology

In brief: Slightly

Because cholesterol synthesis is maximal around midnight if your sleep pattern is normal, and maximal onset of action with Simvastatin is a few hours after taking it, there is a few percentage points benefit for taking it in the evening.
Long acting statins (atorvastatin & rosuvastatin) are less impacted by time of day.

In brief: Slightly

Because cholesterol synthesis is maximal around midnight if your sleep pattern is normal, and maximal onset of action with Simvastatin is a few hours after taking it, there is a few percentage points benefit for taking it in the evening.
Long acting statins (atorvastatin & rosuvastatin) are less impacted by time of day.
Dr. Irv Loh
Dr. Irv Loh
Thank
Get help from a real doctor now
Dr. Tonga Nfor
Board Certified, Internal Medicine - Cardiology
12 years in practice
508K people helped
Continue
108,000 doctors available
Read more answers from doctors