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What is the milnacipran treatment for fibromyalgia?

5 doctors weighed in
Dr. Andrew Ho
Psychiatry
3 doctors agree

In brief: Reuptake inhibitor

Milnacipran blocks reuptake of neurotransmitters serotonin and norepinephrine, thus increasing the availability of those neurotransmitters at neuronal synapses.
The mechanism is similar to duloxetine, which is also indicated for fibromyalgia (and major depression). It is taken orally, 100-200mg per day, and can cause side effects similar to other serotonin reuptake inhibitors (e.g. Fluoxetine).

In brief: Reuptake inhibitor

Milnacipran blocks reuptake of neurotransmitters serotonin and norepinephrine, thus increasing the availability of those neurotransmitters at neuronal synapses.
The mechanism is similar to duloxetine, which is also indicated for fibromyalgia (and major depression). It is taken orally, 100-200mg per day, and can cause side effects similar to other serotonin reuptake inhibitors (e.g. Fluoxetine).
Dr. Andrew Ho
Dr. Andrew Ho
Thank
Dr. Ronald Krauser
Internal Medicine - Rheumatology

In brief: Savella (milnacipran)

The brand name is savella (milnacipran) and this medication is an fda approved therapy for fibromyalgia.

In brief: Savella (milnacipran)

The brand name is savella (milnacipran) and this medication is an fda approved therapy for fibromyalgia.
Dr. Ronald Krauser
Dr. Ronald Krauser
Thank
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