3 doctors weighed in:

How is dapsone induced hemolytic anemia treated?

3 doctors weighed in
Dr. Ritesh Rathore
Internal Medicine - Hematology & Oncology
1 doctor agrees

In brief: Stopping dapsone

The best way to treat Dapsone related anemia is by discontinuing dapsone.
Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid.

In brief: Stopping dapsone

The best way to treat Dapsone related anemia is by discontinuing dapsone.
Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid.
Dr. Ritesh Rathore
Dr. Ritesh Rathore
Thank
Dr. Michael Engel
Pediatrics - Hematology & Oncology

In brief: Generally by ...

Stopping the drug first and foremost.
Dapsone has two primary effects on the blood, both connected to its oxidant qualities. The first is dose-dependent hemolysis, which is more prominent in g6pd deficiency, and the second is methemoglobinenia, where heme fe is oxidized to the +3 oxidation state. Transfusion support may be necessary as a supportive measure.

In brief: Generally by ...

Stopping the drug first and foremost.
Dapsone has two primary effects on the blood, both connected to its oxidant qualities. The first is dose-dependent hemolysis, which is more prominent in g6pd deficiency, and the second is methemoglobinenia, where heme fe is oxidized to the +3 oxidation state. Transfusion support may be necessary as a supportive measure.
Dr. Michael Engel
Dr. Michael Engel
Thank
Get help from a real doctor now
Dr. Vicken Poochikian
Board Certified, Internal Medicine
39 years in practice
2M people helped
Continue
111,000 doctors available
Read more answers from doctors