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What is type 3 von willebrand's disorder?

3 doctors weighed in
Dr. Joseph Torkildson
Pediatrics - Hematology & Oncology
2 doctors agree

In brief: Homozygous vWD

Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein.
Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood.

In brief: Homozygous vWD

Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein.
Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood.
Dr. Joseph Torkildson
Dr. Joseph Torkildson
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Dr. James Ball
Pediatrics - Hematology & Oncology
2 doctors agree

In brief: Bleeding disorder

Type 3 VWD is a bleeding disorder, that results in a complete absence of production of vw factor, which is necessary to initiate the clotting process.
Its absence causes factor 8 to be consumed quickly. Thus, this is a severe bleeding disorder. It is inherited from both parents. It causes nosebleeds, gum bleeding, menstrual bleeding and joint/muscle bleeding. It is treatable.

In brief: Bleeding disorder

Type 3 VWD is a bleeding disorder, that results in a complete absence of production of vw factor, which is necessary to initiate the clotting process.
Its absence causes factor 8 to be consumed quickly. Thus, this is a severe bleeding disorder. It is inherited from both parents. It causes nosebleeds, gum bleeding, menstrual bleeding and joint/muscle bleeding. It is treatable.
Dr. James Ball
Dr. James Ball
Thank
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