What are the most common symptoms of beta-thalassemia major?

Anemia symptoms. The symptoms of beta thalassemia major are those of severe anemia, which include weakness, pallor (pale appearance), decreased growth/development, rapid heart rate, exercise intolerance, thickened bones as the marrow enlarges to try to make more blood cells, enlarged spleen, etc...
Anemia with symptoms. In children anemia is common. appear malnourished , lack energy, failure to thrive, fussiness, poor appetite , jaundice and a large liver and spleen and a bloated abdomen.

Related Questions

Is beta thalassemia major andd hb e/beta thalassemia same?

No. Beta thalassemia is a disorder of hemoglobin. Numerous different mutations can result in altered hemoglobin. In beta thal major, there are two abnormal "beta" genes. In hg e disease due to a specific mutation in the beta chain. In hbe/beta thal, one of the altered genes is hbe and the other is in hbb. Hbe/beta thall can be very variable. Read more...
Not the same. Hemoglobin e is found in the asian population frequently and may be seen with thal trait. Thal major is a serious problem requiring much intervention, including transfusions and frequently splenectomy. Your doctor should be your guiding you. Pregnancy needs to be discussed with your doctor. Read more...