4 doctors weighed in:

Does vitamin B12 deficiency cause brain and nerve problems?

4 doctors weighed in
Dr. Carla Enriquez
Pediatrics
2 doctors agree

In brief: Yes

In the early 19th century, scientists noted weakness and numbness with B12 deficiency.
Recently, B12 has been shown to upregulate neurotrophic factors (chemicals [cytokines] that help nerve cells grow) & downregulate neurotoxic factors (chemicals that break down nerve cells). In other words, B12 helps nerve cells grow and prevents their destruction by naturally occurring brain chemicals.

In brief: Yes

In the early 19th century, scientists noted weakness and numbness with B12 deficiency.
Recently, B12 has been shown to upregulate neurotrophic factors (chemicals [cytokines] that help nerve cells grow) & downregulate neurotoxic factors (chemicals that break down nerve cells). In other words, B12 helps nerve cells grow and prevents their destruction by naturally occurring brain chemicals.
Dr. Carla Enriquez
Dr. Carla Enriquez
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1 doctor agrees

In brief: Yes

It can affect the spinal cord as well.

In brief: Yes

It can affect the spinal cord as well.
Dr. William Shaffer
Dr. William Shaffer
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