5 doctors weighed in:
Who is at risk of getting alpha thalassemia?
5 doctors weighed in

Emily Lu
Family Medicine
2 doctors agree
In brief: Family history
Thalassemia is a genetic disease of the hemoglobin molecule and so only occurs through inheritance.
A mutation in this gene is especially prevalent in persons of african, asian, middle eastern or mediterranean descent. Individuals with only one mutation of the gene will be asymptomatic, so genetic screening is necessary to precisely determine risk.

In brief: Family history
Thalassemia is a genetic disease of the hemoglobin molecule and so only occurs through inheritance.
A mutation in this gene is especially prevalent in persons of african, asian, middle eastern or mediterranean descent. Individuals with only one mutation of the gene will be asymptomatic, so genetic screening is necessary to precisely determine risk.
Emily Lu
Emily Lu
Answer assisted by Emily Lu, Medical Student
Thank
Dr. Robert Kwok
Pediatrics
1 doctor agrees
In brief: High risk ethnicity
Thalassemia is one of the most common gene mutations in the world.
Overall, an estimated 20-25 million people are carriers (1/300) (about 1/1000 in low-risk peoples, and about 1/30 in high-risk peoples). Low risk: japanese, korean, n. European caucasians, native canadians, native americans. High risk: mediterranean, middle eastern, south asian, south-east asian (western pacific rim), caribbean.

In brief: High risk ethnicity
Thalassemia is one of the most common gene mutations in the world.
Overall, an estimated 20-25 million people are carriers (1/300) (about 1/1000 in low-risk peoples, and about 1/30 in high-risk peoples). Low risk: japanese, korean, n. European caucasians, native canadians, native americans. High risk: mediterranean, middle eastern, south asian, south-east asian (western pacific rim), caribbean.
Dr. Robert Kwok
Dr. Robert Kwok
Thank
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