4 doctors weighed in:
Is sam e a good for a natural anti depressant?
4 doctors weighed in

Dr. Pamela Pappas
Psychiatry
3 doctors agree
In brief: SAM-e
Taking sam-e orally can possibly improve the symptoms of depression.
Several clinical studies show sam-e to be more effective than placebo, and at least as effective as tricyclic antidepressants, in trials up to 42 days. Some of these studies are limited by low #'s of patients, inconsistent diagnostic criteria, and short trial length. Dose is 400-1600mg/day -- which can become expensive.

In brief: SAM-e
Taking sam-e orally can possibly improve the symptoms of depression.
Several clinical studies show sam-e to be more effective than placebo, and at least as effective as tricyclic antidepressants, in trials up to 42 days. Some of these studies are limited by low #'s of patients, inconsistent diagnostic criteria, and short trial length. Dose is 400-1600mg/day -- which can become expensive.
Dr. Pamela Pappas
Dr. Pamela Pappas
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