Lupus. Lupus is an autoimmune disease that can afffect any organ system. Most commonly, joints become inflammed (painful and sometimes swollen). Skin rashes are common as well, especially on the face; when distributed over the cheeks , this rash is called a malar rash. Oral ulcers are sometimes noted and fever can be present as well. Pleuritic chest pains that worsen with deep breaths can occur.
Lupus. Systemic lupus erythematosus (sle) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001471/.
can you have SLE diagnosed without auto antibodies in blood work? What are the four critical signs of SLE?
Very unlikely. 98-99% of people who have lupus will have a (+) ANA. If the ANA is (-) then the likelihood of lupus is very remote . In my experience the most helpful signs IF PRESENT are: 1) joint swelling (not pain) 2) A facial/body rash recognizable to someone with experience in recognizing Lupus rashes (there are many mimicks) 3) evidence of kidney disease ( by looking at urine tests) 4) low WBC or platlets. Read more...