3 doctors weighed in:
What does glucosamine have to do with shellfish allergies?
3 doctors weighed in

Dr. Sean McGhee
Internal Medicine - Allergy & Immunology
1 doctor agrees
In brief: Shellfish shells
Glucosamine is manufactured from the shells of shrimp, so contamination with shrimp proteins might cause a reaction.
However, most people who are shellfish allergic are allergic to the muscle of the shrimp, and the amount of the muscle protein in the glucosamine product is small.

In brief: Shellfish shells
Glucosamine is manufactured from the shells of shrimp, so contamination with shrimp proteins might cause a reaction.
However, most people who are shellfish allergic are allergic to the muscle of the shrimp, and the amount of the muscle protein in the glucosamine product is small.
Dr. Sean McGhee
Dr. Sean McGhee
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Dr. Brant Ward
Internal Medicine - Allergy & Immunology
In brief: Not much, but...
Many preparations of glucosamine are prepared from shellfish, so there is a risk that it may be contaminated with the allergens that cause shellfish allergies.
The major allergens in shellfish are chemically different from glucosamine, so there is little risk from pure preparations. Most supplements are not pure, however, so it may be safest to avoid it in cases of severe shellfish allergy.

In brief: Not much, but...
Many preparations of glucosamine are prepared from shellfish, so there is a risk that it may be contaminated with the allergens that cause shellfish allergies.
The major allergens in shellfish are chemically different from glucosamine, so there is little risk from pure preparations. Most supplements are not pure, however, so it may be safest to avoid it in cases of severe shellfish allergy.
Dr. Brant Ward
Dr. Brant Ward
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