How can I make grandma comfortable in her new assited living facility?

Normalize. Transition to any new living environment is one of lifes biggest stressors, at any age. Losing one's independence is especially hard as we age. Make grandmom's living spce as home like as you can. Familiar pictures, furniture, etc. If she has memory impairment, thsi is most important. Other things that she enjoys should be encouraged(music, etc).