Generally benign. May or may not numb up the skin before inserting a thin needed through the skin into your thyroid and sucking out cells and fluid. You should discuss this in advance with whomever is scheduled to perform your biopsy.
Simple Procedure. Thyroid nodule fna is usually an easy procedure for patients. Many will do it under u/s guidance. The needle is very tiny. Some may even numb the area before the fna. It doesn't really hurt, but there can be referred discomfort to the inside of the ear on that side until the needle is pulled back. A few samples are necessary. After, the area may be a little puffy & sore to touch for a day or so.