10 doctors weighed in:
Why does your IgE level increase when you have asthma?
10 doctors weighed in

Dr. Steven Machtinger
Internal Medicine - Allergy & Immunology
4 doctors agree
In brief: High IgE more asthma
Ige is a type of antibody with a pivotal role in allergic conditions like asthma.
Each ige antibody is specific for a thing - dust mite, cat, pollen or peanut. On mast cells throughout the body ige receptors bind ige. If an allergen like cat dander enters your body combining with ige that recognizes it on lung mast cells the result is asthma. Increased asthma risk associated with high ige levels.

In brief: High IgE more asthma
Ige is a type of antibody with a pivotal role in allergic conditions like asthma.
Each ige antibody is specific for a thing - dust mite, cat, pollen or peanut. On mast cells throughout the body ige receptors bind ige. If an allergen like cat dander enters your body combining with ige that recognizes it on lung mast cells the result is asthma. Increased asthma risk associated with high ige levels.
Dr. Steven Machtinger
Dr. Steven Machtinger
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Dr. Arvind Madaan
Internal Medicine - Allergy & Immunology
4 doctors agree
In brief: Asthma Control
Agree with previous answer explaining "allergic tendency" or "atopy" and the role of ige in disease expression.
If asthma is not controlled despite high dose inhaled steroids with/without long acting bronchodilators, level of ige and presence of year-round allergen sensitivity may also be used to determine your candidature for monoclonal antibody - omalizumab. Please check with your allergist.

In brief: Asthma Control
Agree with previous answer explaining "allergic tendency" or "atopy" and the role of ige in disease expression.
If asthma is not controlled despite high dose inhaled steroids with/without long acting bronchodilators, level of ige and presence of year-round allergen sensitivity may also be used to determine your candidature for monoclonal antibody - omalizumab. Please check with your allergist.
Dr. Arvind Madaan
Dr. Arvind Madaan
Thank
Dr. James Sublett
Internal Medicine - Allergy & Immunology
2 doctors agree
In brief: Allergy
Ige is the allergy antibody.
It is elevated in individuals with allergy. Allergies are a common cause of asthma. The tendency to have allergies is called "atopy" and is a function of genetics. An atopic person, when exposed to things that cause allergies, makes specific ige antibody against that substance. For instance, someone allergic to cat will have high ige antibody to cat.

In brief: Allergy
Ige is the allergy antibody.
It is elevated in individuals with allergy. Allergies are a common cause of asthma. The tendency to have allergies is called "atopy" and is a function of genetics. An atopic person, when exposed to things that cause allergies, makes specific ige antibody against that substance. For instance, someone allergic to cat will have high ige antibody to cat.
Dr. James Sublett
Dr. James Sublett
Thank
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