4 doctors weighed in:

How long do corticosteroids remain in your system?

4 doctors weighed in
Dr. Alex Martinez
Internal Medicine - Allergy
2 doctors agree

In brief: Days to weeks

Corticosteroids are made naturally in our bodies and are involved in the regulation of inflammation.
Because of this, all cells in our bodies have receptors for these compounds. When a corticosteroid is prescribed (topical, oral, or by injection), how long it remains is dependent on how quickly it is metabolized. Usually corticosteroids are metabolized in days but occasionally in weeks.

In brief: Days to weeks

Corticosteroids are made naturally in our bodies and are involved in the regulation of inflammation.
Because of this, all cells in our bodies have receptors for these compounds. When a corticosteroid is prescribed (topical, oral, or by injection), how long it remains is dependent on how quickly it is metabolized. Usually corticosteroids are metabolized in days but occasionally in weeks.
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Dr. Jack Mutnick
Internal Medicine - Allergy & Immunology

In brief: Depends

You need to look at the half-life of the steroid.
Hydrocortisone has a half-life of 8-12 hours. Medrol (methylprednisolone) is 18-36 hours. Prednisone is 18-36 hours. Dexamethasone is 36-54 hours.

In brief: Depends

You need to look at the half-life of the steroid.
Hydrocortisone has a half-life of 8-12 hours. Medrol (methylprednisolone) is 18-36 hours. Prednisone is 18-36 hours. Dexamethasone is 36-54 hours.
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