Interconnected. Sleep deprivation can lead to being really tired. We need 7-8 hours of uninterrupted sleep to recharge nightly. This is when our hormones and secreted. If we don't do that well over a length of time the body starts to wear down and fatigue sets in. Chronic fatigue is caused by various issues. Go to a4m.Com and use doctor locator to find a local functional medicine doctor to help you find the cause.