6 doctors weighed in:
Why does Excedrin always seem to cure my moody depression?
6 doctors weighed in

Dr. Lawrence Smith
Clinical Psychology
3 doctors agree
In brief: "Secret ingredient"
It could be the caffeine in the excedrine.
It is possible that it is addressing some degree of caffeine withdrawal or just alleviating mild symptoms of fatigue, depressed mood, or irritability. Excedrine contains nearly the same caffeine as a shot of espresso.

In brief: "Secret ingredient"
It could be the caffeine in the excedrine.
It is possible that it is addressing some degree of caffeine withdrawal or just alleviating mild symptoms of fatigue, depressed mood, or irritability. Excedrine contains nearly the same caffeine as a shot of espresso.
Dr. Lawrence Smith
Dr. Lawrence Smith
Thank
Dr. Paul Pyles
Addiction Medicine
1 doctor agrees
In brief: Great Question
Excedrin contains caffeine, aspirin, and acetaminophen.
It is possible that you are benefiting from the stimulating effect of the caffeine along with the anti-inflammatory and analgesic effects of the acetaminophen and aspirin helping you to feel better.

In brief: Great Question
Excedrin contains caffeine, aspirin, and acetaminophen.
It is possible that you are benefiting from the stimulating effect of the caffeine along with the anti-inflammatory and analgesic effects of the acetaminophen and aspirin helping you to feel better.
Dr. Paul Pyles
Dr. Paul Pyles
Thank
Get help from a real doctor now
Dr. Eric Weisman
Board Certified, Neurology
32 years in practice
9M people helped
Continue
108,000 doctors available
Read more answers from doctors