How does medicinal nitroglycerin for angina affect you?

Dilates vessels. It dilates blood vessels and lowers blood pressure. Burning under the tongue and headache are normal for new users. Esophageal smooth muscle is also affected so relief of pain is not specific for heart disease. Effects occur 2-3 minutes after a sublingual dose and last 20-30 minutes. Gi pain often requires 2 or 3 nitros for full relief.