Brain Connectivity. Think of the brain consisting of an inner core where our most basic emotions and impulses lie and an outer layer consisting of rational thought that can modulate emotion. These layers are connected. Rtms stimulates the outer layer which is most directly connected with the inner core associated w/ depressed mood. Tms can stimulate to enhance mood or inhibit to reduce depressed mood via the connection.
RTMS. Repetitive transcranial magnetic stimulation (rtms) is a brain stimulation treatment that targets a specific spot in the brain. Scientists believe that this specificity may provide an advantage over ECT (which is effective but has mild side effects). A typical rtms session lasts 30 to 60 minutes and does not require anesthesia. Short electromagnetic pulses do the work.
Dual mechanism. It is thought that tms has both "local" and "distal" (or distance) effects. Local effects result in the release of neurotransmitters from neurons close to the brain's surface right under the tms treatment coil. There are also so-called "pyramidal cells" there, with axons that project to deep brain nuclei. Stimulating these triggers release of neurotransmitters from these nuclei.
TMS Experience. A magnet the shape of the cup of your hand is gently placed on the scalp near the temple area, overlying the frontal lobe of the brain. Short 4 second pulses, with 26 second rest intervals, are applied. This happens for about 40 minutes, 5 days a week for a number of weeks. Pulses sound like a loud typewriter, and while they initially may cause discomfort, most patients acclimate quickly.
Several Mechanisms. There are a variety of areas in the brain that are affected during depression. It is evident through decreased activity smaller volume and abnormal oscillations. What tms does is directly connect with these networks of neurons and activate them electrically causing them to normalize. Doing this on a daily basis normalizes their activity. Http://advancedmentalhealth. Com/tms.
Mixed results. According to a nimh review, clinical trials studying the effectiveness of repetitive transcranial magnetic stimulation (rtms) have had mixed results. Some studies have found that rtms is more effective in treating patients with major depression. But, other studies have found no difference in response to rtms compared to inactive treatment.
Looks promising. Refractory depression is often hard to treat. Tms offers a safe but expensive treatment which can be offered following failure to just one antidepressant. The treatments are usually 5 days a week and go on for 4-5 weeks in the parts of dallas I am familiar with. I wish insurance would cover this more often.
Absolutely. Research shows that tms, when used alone without meds, is as effective as a 1st trial of an antidepressant drug, and more effective than trying a 2nd one. Using tms as an add-on to meds can be even more effective. As a psychiatrist who treats patients with tms and medications in los angeles, I feel very comfortable using both, either separately or in combination, depending on patient needs.
TMS. Yes, more so when used in combination with antidepressants.
Yes. Yes. I believe, particularly after seeing it in our patients, that it is the most potent, best tolerated procedure. In my estimation, it is as effective as electroconvulsive therapy.... You just have to wait a few weeks to a few months after treatment is concluded. It is not as fast, but is remarkably better tolerated with no memory loss. It is also more potent than medications.