How come nothing I use clears up my acne?

Don't give up. Acne can be frustrating to treat. However, usually we can find a treatment regimen to help most patients. See a dermatologist, who can help determine what treatment(s) might be best for you. Bring a list of all the things you've tried, along with doses and how long you tried them. If you've been under the care of a dermatologist, be sure they know you aren't better. Can consider a 2nd opinion.