What could cause itchy spots and lip swelling?

Poss allergy. Take note of what you eat that causes it.
Possible allergy. If it happens afte/while eating a particular, you could have a food allergy.

Related Questions

I am experiencing skin rash (quality: itchiness, bumpy) and lip swelling. The following also describes me: Hives (Urticaria). What should I do?

Maybe related. This may all be manifestations of your urticaria. You will need to have clarification as to why you have urticaria. This is something you can evaluate with your physician and possibly a specialist such as a dermatologist or an allergist.