2 doctors weighed in:

What is the pathogenesis of atherosclerosis?

2 doctors weighed in
Dr. Milton Alvis Jr
Preventive Medicine

In brief: White Blood Cells

White blood cells, mostly macrophages, invade into the walls of the blood vessel to remove low density lipoprotein (fat carrying protein) particles.
Macrophages die if overwhelmed with ingested fat molecules & cannot export ingested fat into high density lipoprotein particles. Elevated glucose & blood pressure, even mild, genetics, inactivity, smoking, sugars, not resolving emotional stress, etc.

In brief: White Blood Cells

White blood cells, mostly macrophages, invade into the walls of the blood vessel to remove low density lipoprotein (fat carrying protein) particles.
Macrophages die if overwhelmed with ingested fat molecules & cannot export ingested fat into high density lipoprotein particles. Elevated glucose & blood pressure, even mild, genetics, inactivity, smoking, sugars, not resolving emotional stress, etc.
Dr. Milton Alvis Jr
Dr. Milton Alvis Jr
Thank
Dr. Shadi Abu Halimah
Surgery - Vascular

In brief: Multifactorial

Disease in the media( middle layer) of the artery with accumulation of fat, cholesterol into the wall causing inflammation which become chronic with special white blood cells called macrophages.
Sometimes become calcified and sometimes can ulcerate or rupture into arterial lumen inducing emboli or clot/ thrombosis.

In brief: Multifactorial

Disease in the media( middle layer) of the artery with accumulation of fat, cholesterol into the wall causing inflammation which become chronic with special white blood cells called macrophages.
Sometimes become calcified and sometimes can ulcerate or rupture into arterial lumen inducing emboli or clot/ thrombosis.
Dr. Shadi Abu Halimah
Dr. Shadi Abu Halimah
Thank
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