2 doctors weighed in:
Are congenital heart defects hereditary?
2 doctors weighed in

Dr. James Ferguson
Pediatrics
In brief: Depends on variables
There are a few syndromes with high frequency of specific heart defects that can have inheritance risk up to 50%.
Most, however, are part of a complex inheritance pattern with around 5% risk.This 5% would include any pattern of congenital heart defect, not necessarily the same one.

In brief: Depends on variables
There are a few syndromes with high frequency of specific heart defects that can have inheritance risk up to 50%.
Most, however, are part of a complex inheritance pattern with around 5% risk.This 5% would include any pattern of congenital heart defect, not necessarily the same one.
Dr. James Ferguson
Dr. James Ferguson
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Dr. Nikolaos Zacharias
Obstetrics & Gynecology - Maternal Fetal Medicine
In brief: They can be.
Multifactorial inheritance is seen with most congenital defects (including cardiac), meaning they more likely to recur in future pregnancies if the first one is affected (or if the mother or father is affected).
Obviously, syndromic cases will have stronger genetic inheritance and more mendelian vertical transmission.

In brief: They can be.
Multifactorial inheritance is seen with most congenital defects (including cardiac), meaning they more likely to recur in future pregnancies if the first one is affected (or if the mother or father is affected).
Obviously, syndromic cases will have stronger genetic inheritance and more mendelian vertical transmission.
Dr. Nikolaos Zacharias
Dr. Nikolaos Zacharias
Thank
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