8 doctors weighed in:

What are the differences between valproic acid and lithium?

8 doctors weighed in
Dr. Paul Pancner
Clinical Psychology
7 doctors agree

In brief: Considerable

Although Depakote and lithium are both prescribed and are effective for the treatment of bipolar d/o, they do differ.Depakote is actually an anticonvulsant medication prescribed for seizures, while lithium is not.
The latter is basically a mineral and considered a mood stabilizing medication. Lithium is metabolized through the kidneys, while Depakote is through the liver.

In brief: Considerable

Although Depakote and lithium are both prescribed and are effective for the treatment of bipolar d/o, they do differ.Depakote is actually an anticonvulsant medication prescribed for seizures, while lithium is not.
The latter is basically a mineral and considered a mood stabilizing medication. Lithium is metabolized through the kidneys, while Depakote is through the liver.
Dr. Paul Pancner
Dr. Paul Pancner
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