How do you get a positive leukocyte esterase result from antibiotic induced tubulointerstitial nephritis?

Inflammation cells. Antibiotic induced interstitial nephritis causes an inflammatory reaction in the kidney between nephron tubules which drain the glomeruli (microscopic filters) these inflammation white blood cells work their way into lumen of damaged interstitial tubules & thus into urine which will give a positive leucocyte esterase result. Latter is test for wbcs in urine.

Related Questions

How to get a positive leukocyte esterase result from drug induced (antbiotic) tubulointerstitial nephritis?

Normal Occurrence. Leukocyte Esterase simply means the presence of WBCs. Drug-induced nephritis is partly an inflammatory response and that means the presence of WBCs. Once the nephritis clears up the leukocyte esterase should also clear up. Read more...