How is leptospirosis transmitted and how is it treated?

Surroundings. Humans most often become infected after exposure to environmental sources, such as animal urine, contaminated water or soil, or infected animal tissue. Portals of entry include cuts or abraded skin, mucous membranes or conjunctiva. The vast majority of infections with leptospira are self-limiting. Although penicillins, tetracyclines, chloramphenicol, and Erythromycin have antileptospiral activity.