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Loratidine stopped working. Should I switch or add something else, like zyrtec (cetirizine)?
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Dr. Barbara Stark Baxter
Internal Medicine - Allergy & Immunology
In brief: Zyrtec vs claritin (loratadine)
Loratidine (claritin) is the most ineffective antihistamine ever approved for market.
Its effect is weak and can take a long time to work. Zyrtec is stronger but a little more sedating, 13% vs 8% (loratidine). It can be taken alone or in combination with loratidine or fexofenadine. The latter is the least sedating of the three and about as potent as cetirizine.

In brief: Zyrtec vs claritin (loratadine)
Loratidine (claritin) is the most ineffective antihistamine ever approved for market.
Its effect is weak and can take a long time to work. Zyrtec is stronger but a little more sedating, 13% vs 8% (loratidine). It can be taken alone or in combination with loratidine or fexofenadine. The latter is the least sedating of the three and about as potent as cetirizine.
Dr. Barbara Stark Baxter
Dr. Barbara Stark Baxter
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