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How would you diagnose someone with a gluten sensitivity if it doesn't show up in their routine bloodwork?

2 doctors weighed in
Dr. Arthur Heller
Internal Medicine - Gastroenterology
1 doctor agrees

In brief: Specialized tests

Routine bloodwork doesn't test for celiac sprue (gluten enteropathy), but may pick up the effects of it, e.
g. Anemia, vitamin d deficiency. True gluten sensitivity can be screened with a number of blood tests, including deamidated gliadin, transglutaminase antibodies; genetic testing helpful to exclude the condition. Biopsy of small bowel to confirm the diagnosis.

In brief: Specialized tests

Routine bloodwork doesn't test for celiac sprue (gluten enteropathy), but may pick up the effects of it, e.
g. Anemia, vitamin d deficiency. True gluten sensitivity can be screened with a number of blood tests, including deamidated gliadin, transglutaminase antibodies; genetic testing helpful to exclude the condition. Biopsy of small bowel to confirm the diagnosis.
Dr. Arthur Heller
Dr. Arthur Heller
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