2 doctors weighed in:
What is the difference between weight-based and fixed dose of pegylated interferon?
2 doctors weighed in

Dr. Jack Mutnick
Internal Medicine - Allergy & Immunology
In brief: Interferon
Weight based means that the dose is adjusted for the milligrams per kilogram of the patient whereas a fixed dose simply means everybody, no matter age or weight or gender, gets the exact same dose.

In brief: Interferon
Weight based means that the dose is adjusted for the milligrams per kilogram of the patient whereas a fixed dose simply means everybody, no matter age or weight or gender, gets the exact same dose.
Dr. Jack Mutnick
Dr. Jack Mutnick
Thank
Dr. Brett Kalmowitz
Internal Medicine - Gastroenterology
In brief: Different meds
Peg-intron (alpha 2b) is given as a weight based medication.
Pegasys (peginterferon alfa 2a) (alpha 2a) is given as a fixed dose. The difference has to do with the distribution throughout the tissues and fats of the body. Most docs think the 2 are comparable clinically as long as they are dosed appropriately. If using for treatment of hepatitis c, they should be used in combination with 1 or 2 other meds for best results.

In brief: Different meds
Peg-intron (alpha 2b) is given as a weight based medication.
Pegasys (peginterferon alfa 2a) (alpha 2a) is given as a fixed dose. The difference has to do with the distribution throughout the tissues and fats of the body. Most docs think the 2 are comparable clinically as long as they are dosed appropriately. If using for treatment of hepatitis c, they should be used in combination with 1 or 2 other meds for best results.
Dr. Brett Kalmowitz
Dr. Brett Kalmowitz
Thank
Get help from a real doctor now
Dr. Steven Seres
Board Certified, Internal Medicine
17 years in practice
497K people helped
Continue
108,000 doctors available
Read more answers from doctors