6 doctors weighed in:

If sexual dysfunction of ssri's is caused by serotonin, then why can atomoxetine cause it too?

6 doctors weighed in
Dr. Foster Carr
General Practice
5 doctors agree

In brief: Different actions

Amoxetine is a norepinephrine reuptake inhibitor while ssri's are serotonin reuptake inhibitors.
They have effects on different systems although the side effects on sexual dysfunction can be the same. One way to think about it is that two different autonomic nervous systems required for proper function (sympathetic and cholinergic). If either system is not working then dysfunction can occur.

In brief: Different actions

Amoxetine is a norepinephrine reuptake inhibitor while ssri's are serotonin reuptake inhibitors.
They have effects on different systems although the side effects on sexual dysfunction can be the same. One way to think about it is that two different autonomic nervous systems required for proper function (sympathetic and cholinergic). If either system is not working then dysfunction can occur.
Dr. Foster Carr
Dr. Foster Carr
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