2 doctors weighed in:
Explain the blindness from levels of high oxygen when given to a premature infant?
2 doctors weighed in

Dr. James Ferguson
Pediatrics
In brief: Environment
The environment that produces normal eyes is the womb.
While in the womb, baby's eyes get about 60% blood oxygen content. Early work with premi's included putting them in "incubators" & piping in oxygen, hoping that they survived.Testing blood gasses was almost impossible, but when obtained,O2 use was geared at keeping above 90%.Now they keep it lower.The high blood oxygen triggered damage in some

In brief: Environment
The environment that produces normal eyes is the womb.
While in the womb, baby's eyes get about 60% blood oxygen content. Early work with premi's included putting them in "incubators" & piping in oxygen, hoping that they survived.Testing blood gasses was almost impossible, but when obtained,O2 use was geared at keeping above 90%.Now they keep it lower.The high blood oxygen triggered damage in some
Dr. James Ferguson
Dr. James Ferguson
Thank
Dr. Benjamin Nguyen
Anesthesiology
In brief: Oxygen free radicals
Oxygen in high concentrations cause oxygen to breakdown and form oxygen free radicals which can damage cells in the body.
In premature infants, this can lead to what is called retinopathy of prematurity.

In brief: Oxygen free radicals
Oxygen in high concentrations cause oxygen to breakdown and form oxygen free radicals which can damage cells in the body.
In premature infants, this can lead to what is called retinopathy of prematurity.
Dr. Benjamin Nguyen
Dr. Benjamin Nguyen
Thank
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