5 doctors weighed in:
Can men with sickle cell disease have healthy children?
5 doctors weighed in

Dr. James Ball
Pediatrics - Hematology & Oncology
3 doctors agree
In brief: Yes.
Sickle cell disease must be inherited from both parents.
So it depends on the mother of the child. If she has sickle cell - all of your children will have sickle cell. If she has sickle cell trait - there is a 50% chance your children will have sickle cell disease, and a 50% chance of your children having sickle cell trait. If she has no sickle cell - your children will have sickle cell trait.

In brief: Yes.
Sickle cell disease must be inherited from both parents.
So it depends on the mother of the child. If she has sickle cell - all of your children will have sickle cell. If she has sickle cell trait - there is a 50% chance your children will have sickle cell disease, and a 50% chance of your children having sickle cell trait. If she has no sickle cell - your children will have sickle cell trait.
Dr. James Ball
Dr. James Ball
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Dr. Randolph Thomas
Pediatrics
1 doctor agrees
In brief: Yes
The children are likely to be healthy as long as the children's mother doesn't have sickle cell trait, some other abnormal hemoglobin trait or a thalassemia.
An expectant couple with one partner with sickle cell anemia should see a genetic counselor and have the partner tested for hemoglobinopathies and thallasemias prior to conception.

In brief: Yes
The children are likely to be healthy as long as the children's mother doesn't have sickle cell trait, some other abnormal hemoglobin trait or a thalassemia.
An expectant couple with one partner with sickle cell anemia should see a genetic counselor and have the partner tested for hemoglobinopathies and thallasemias prior to conception.
Dr. Randolph Thomas
Dr. Randolph Thomas
Thank
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