2 doctors weighed in:

What goes wrong with the protein that leads to primary ciliary dyskinesia ?

2 doctors weighed in
Dr. Lokesh Guglani
Pediatrics - Pulmonology
1 doctor agrees

In brief: Structural defect

There are 11 genetic mutations known to cause PCD & they all affect the structure of cilia (or tiny hair like structures on top of cells in various parts of our body) in different ways.
The result is disordered/absent ciliary movement leading to problems with clearing infectious bugs that are normally eliminated by this mucociliary escalator, esp in lungs. Other effects are on body cells also occu.

In brief: Structural defect

There are 11 genetic mutations known to cause PCD & they all affect the structure of cilia (or tiny hair like structures on top of cells in various parts of our body) in different ways.
The result is disordered/absent ciliary movement leading to problems with clearing infectious bugs that are normally eliminated by this mucociliary escalator, esp in lungs. Other effects are on body cells also occu.
Dr. Lokesh Guglani
Dr. Lokesh Guglani
Thank
Read more answers from doctors