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Why would a patient with diabetes mellitus 2 have high triglycerides level?

2 doctors weighed in
Dr. William Cromwell
Clinical Lipidology

In brief: Metabolic Disorder

High triglyceride (tg) in t2dm results from increased tg synthesis and decreased clearance of tg-rich lipoproteins.
Free fatty acids, liberated from fat cells, amplify tg synthesis in the liver. High glucose and carb intake worsen this process. Liver tg is packed into vldl particles and exported to the circulation where lipases degrade tg-rich particles. Lipase function is decreased in t2dm.

In brief: Metabolic Disorder

High triglyceride (tg) in t2dm results from increased tg synthesis and decreased clearance of tg-rich lipoproteins.
Free fatty acids, liberated from fat cells, amplify tg synthesis in the liver. High glucose and carb intake worsen this process. Liver tg is packed into vldl particles and exported to the circulation where lipases degrade tg-rich particles. Lipase function is decreased in t2dm.
Dr. William Cromwell
Dr. William Cromwell
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Dr. Louis Krenn
Family Medicine

In brief: Too much sugar

Diabetics often have too much sugar in their blood.
The body tries to either use this sugar or store it, but due to Insulin resistance it is not able to properly do either. The excess sugar is then changed to fatty acids that are then used to create triglycerides. Most type 2 diabetics are also obese, which is associated with high triglycerides.

In brief: Too much sugar

Diabetics often have too much sugar in their blood.
The body tries to either use this sugar or store it, but due to Insulin resistance it is not able to properly do either. The excess sugar is then changed to fatty acids that are then used to create triglycerides. Most type 2 diabetics are also obese, which is associated with high triglycerides.
Dr. Louis Krenn
Dr. Louis Krenn
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